Emit Xerra
The Xerra is a next generation cryo-fluorescence tomography tool that allows for comprehensive 3D fluorescence & anatomical images from 2D images. The Xerra does not require any radio-labeling and is located only inside the ARCF facility.
Features and Benefits:
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Superior resolution down to 20 um and up to 100 um in sections from 10 um to 50 um in thickness
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High sensitivity to detect signals deep in tissue with an optical field of view of maximum 24 x 14 cm and minimum of 8 x 5 cm
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High throughput, with the capacity to process several mice or multiple dissected organs on the same block
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Reduces data variability by combining CFT with in vivo imaging and tissue microscopy from the same animal for reconstruction of whole body/tissue data in white and fluorescent light images
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Streamlined user process, with no fixation, perfusion, tissue clearing, or radio-labeling required
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Ability to select specific slices and transfer onto histology tape for further analysis
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Maintains complete anatomical context with a single machine
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Allows for versatile visualization from 470-780 nm
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Automated workflows that obtain automated reconstructions of 2D slices into 3D as well as map exact anatomical location of molecular imaging data
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Has integrated software and an onboard computer that allows for fast quantitative analysis, import/export function and provides access to open source data that can be integrated with iPACS
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Applications:
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High resolution visualization of cell clusters, isolated organs and whole animals
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Visualization of vector distribution & vector mediated gene expression
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If you are interested in using the Xerra, please contact Darshini (dvijay26@uw.edu) for more information about pricing.