Xiaoming Yang, M.D., Ph.D.

Professor
Director, Image-Guided Bio-Molecular Interventions Research
Interventional Radiology

Biography

Dr. Yang is a UW professor and director of image-guided bio-molecular interventions research in the Department of Radiology at the University of Washington School of Medicine. He is also an attending physician of interventional radiology at UW Medical Center, and holds an appointment as a senior lecturer of radiology at Kuopio University in Finland and as an attending physician of radiology qualified in European community countries.
 
Dr. Yang received his M.D. in 1983 from Suzhou University School of Medicine, China. He then received a master’s degree of medical science in 1986 from the Chinese Academy of Medical Sciences and Peking Union Medical University in Beijing, followed by a Ph.D. of medical science in 1991 from Kuopio University, Finland.
 
Dr. Yang completed his residencies in radiology at Peking Union Hospital in Beijing and Kuopio University Hospital in Finland, followed by post-doctoral fellowships at Johns Hopkins University and the University of Washington. In 2002, Dr. Yang was appointed associate professor and co-director of the Center for Image-Guided Interventions at Johns Hopkins University School of Medicine.
 
Because of his special background of both a physician and a scientist, Dr. Yang is functioning as a unique “bridge” linking bench research and clinical practice. Dr. Yang has received over $12,000,000 in funding from US National Institutes of Health (NIH) and other funding agencies. As one of the pioneers, Dr. Yang has created several new concepts and technologies on medical imaging and interventional radiology in the world, including developments of intraluminal MR imaging and interventions, MRI-tracking of stem cells in vascular diseases, imaging of vascular gene therapy, and interventional molecular imaging.

Awards and Honors

• Chinese Society of Radiology 2017 Gold Medal — Honorary Member, October 15, 2017
• Chinese Society of Interventional Radiology 2017 Outstanding Physician – Scientist Award, October 15, 2017

Recent Publications

See all publications on Scopus

Orthotopic hepatocellular carcinoma: molecular imaging-monitored intratumoral hyperthermia-enhanced direct oncolytic virotherapy
Song J., Zhang F., Ji J., Chen M., Li Q., Weng Q., Gu S., Kogut M., Yang X.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2019 Jan:344-350

Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53
Zhou F., Zhang Y., Xu X., Luo J., Yang F., Wang L., Xie S., Sun J., Yang X.
Cancer Cell International. 2018 Aug

Non–Small-Cell lung cancer: Feasibility of intratumoral radiofrequency hyperthermia–enhanced herpes simplex virus thymidine kinase gene therapy
Ji J., Weng Q., Zhang F., Xiong F., Jin Y., Hui J., Song J., Gao J., Chen M., Li Q., Shin D., Yang X.
Radiology. 2018 Aug:612-620

Fe3+@polyDOPA- b-polysarcosine, a T1-Weighted MRI Contrast Agent via Controlled NTA Polymerization
Miao Y., Xie F., Cen J., Zhou F., Tao X., Luo J., Han G., Kong X., Yang X., Sun J., Ling J.
ACS Macro Letters. 2018 Jun:693-698

Casein kinase 1α: Biological mechanisms and theranostic potential
Jiang S., Zhang M., Sun J., Yang X.
Cell Communication and Signaling. 2018 May

Orthotopic hepatic cancer: Radiofrequency hyperthermiaenhanced intratumoral herpes simplex virus-thymidine kinase gene therapy
Xiong F., Zhang F., Jin Y., Weng Q., Song J., Zhou G., Shin D., Zheng C., Yang X.
Oncotarget. 2018 Jan:14099-14108

Intratumoral radiofrequency hyperthermia-enhanced chemotherapy of liposomal doxorubicin on hepatocellular carcinoma

American Journal of Translational Research. 2018 Jan:3619-3627

Radiofrequency heat-enhanced direct intratumoral chemotherapy for prostate cancer
Wu X., Zhang F., Hu P., Chen L., Han G., Bai W., Luo J., Chen R., Zhou Y., Sun J., Yang X.
Oncology Letters. 2017 Dec:7250-7256

Science to practice: Enhancing photothermal ablation of colorectal liver metastases with targeted hybrid nanoparticles
Yang X.
Radiology. 2017 Dec:699-701

Radiofrequency hyperthermia-enhanced herpes simplex virus-thymidine kinase/ganciclovir direct intratumoral gene therapy of hepatocellular carcinoma
Wang J., Shi Y., Bai Z., Li Y., Qiu L., Johnson G., Zhang F., Yang X.
International Journal of Hyperthermia. 2017 Feb:170-177