Radiology Personnel

Swati Rane, Ph.D.

Assistant Professor


The primary focus of my research is the development of novel perfusion imaging approaches to better understand cerebrovascular pathology. Specifically, I am interested in investigating the relation of hemodynamic factors such as cerebral blood flow (CBF) and cerebral blood volume (CBV) as well as metabolic demands or oxygen metabolism (CMRO2) to neural activity in degenerative diseases.

My areas of interest are:

  • Arterial spin labeling MRI and development of novel imaging paradigms related to cerebral perfusion
  • Degenerative diseases especially, Alzheimer’s Disease
  • Application of machine learning approaches to imaging data in order to improve disease characterization


Recent Publications

See all publications on Scopus

Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults
Jefferson A., Cambronero F., Liu D., Moore E., Neal J., Terry J., Nair S., Pechman K., Rane S., Davis L., Gifford K., Hohman T., Bell S., Wang T., Beckman J., Carr J.
Circulation. 2018 Oct:1951-1962

Multisite concordance of DSC-MRI analysis for brain tumors: Results of a National Cancer Institute Quantitative Imaging Network Collaborative Project
Schmainda K., Prah M., Rand S., Liu Y., Logan B., Muzi M., Rane S., Da X., Yen Y., Kalpathy-Cramer J., Chenevert T., Hoff B., Ross B., Cao Y., Aryal M., Erickson B., Korfiatis P., Dondlinger T., Bell L., Hu L., Kinahan P., Quarles C.
American Journal of Neuroradiology. 2018 Jun:1008-1016

Quantitative cerebrovascular pathology in a community-based cohort of older adults
Rane S., Koh N., Boord P., Madhyastha T., Askren M., Jayadev S., Cholerton B., Larson E., Grabowski T.
Neurobiology of Aging. 2018 May:77-85

Amnestic mild cognitive impairment individuals with dissimilar pathologic origins show common regional vulnerability in the default mode network
Rane S., Donahue M., Claassen D.
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 2018 Jan:717-725

MRI techniques to measure arterial and venous cerebral blood volume
Hua J., Liu P., Kim T., Donahue M., Rane S., Chen J., Qin Q., Kim S.
NeuroImage. 2018 Jan

Lower cardiac index levels relate to lower cerebral blood flow in older adults
Jefferson A., Liu D., Gupta D., Pechman K., Watchmaker J., Gordon E., Rane S., Bell S., Mendes L., Davis L., Gifford K., Hohman T., Wang T., Donahue M.
Neurology. 2017 Dec:2327-2334

Cortical asymmetry in Parkinson’s disease: early susceptibility of the left hemisphere
Claassen D., McDonell K., Donahue M., Rawal S., Wylie S., Neimat J., Kang H., Hedera P., Zald D., Landman B., Dawant B., Rane S.
Brain and Behavior. 2016 Dec

Hippocampal arterial cerebral blood volume in early psychosis
Talati P., Rane S., Donahue M., Heckers S.
Psychiatry Research - Neuroimaging. 2016 Oct:21-25

Inflow-vascular space occupancy (iVASO) reproducibility in the hippocampus and cortex at different blood water nulling times
Rane S., Talati P., Donahue M., Heckers S.
Magnetic Resonance in Medicine. 2016 Jun:2379-2387

The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview
Jefferson A., Gifford K., Acosta L., Bell S., Donahue M., Davis L., Gottlieb J., Gupta D., Hohman T., Lane E., Libon D., Mendes L., Niswender K., Pechman K., Rane S., Ruberg F., Su Y., Zetterberg H., Liu D.
Journal of Alzheimer's Disease. 2016 May:539-559