UW OncoRad / Tumor Imaging Metrics Core (TIMC)
The University of Washington (UW) OncoRad service has provided imaging assessments of response for patients on oncology clinical trials since February 2009. Assessments are performed by UW radiologists. Since September 2014, assessments have been performed using a web-based application developed and supported by the Dana-Farber/Harvard Cancer Center Tumor Imaging Metrics Core (TIMC). The OncoRad service is a Federally mandated Cost Center and as such must charge all users the same fee for the same service. The service is available to UW investigators and members of the Fred Hutchinson/University of Washington Cancer Consortium.
Imaging response assessments for patients in clinical trials are considered a research service. Tumor measurements from scans (CT, MR, PET/CT, bone scan) for these patients are completed at each scanning time point dictated by the study protocol and independent of whether the scan itself is considered usual care or research care. Read requests (i.e., requests for reports using the desired response criteria) must be entered in OncoRad/TIMC on behalf of the requesting UW or FHCRC physician. The OncoRad/TIMC reports are separate and independent of the clinical reports. Each report provides an assessment using only one response criteria. For study protocols using more than one response criteria, separate simultaneous reports are provided for each criteria and there is a separate charge for each criteria (report) requested at each time point.
Carolyn L. Wang, MD
Ryan B. O’Malley, MD
UW radiologists provide interpretation and reporting of common tumor assessment criteria used in oncology clinical trials, including but not limited to:
- RECIST 1.0
- RECIST 1.1
- Cheson 99
- Revised Cheson 2007
- Cheson 2014 (Lugano)
- irRECIST 1.1
- PCWG2 with RECIST 1.1
Standard criteria may be modified by the sponsor or investigator to meet the specific needs of the protocol.
- Initial fee for setting up each evaluation criteria (with additional charges for protocols requiring assessments using more than one criteria at each time point). There is also an additional fee for modifications to the standard published criteria.
- Fee for each assessment (report) at each time point. Fees are based on the complexity of the criteria and the tools/expertise needed to complete the case.
- Rush fee for providing reports in less than 4 hours (reporting hours are weekdays 9am-5pm); applicable only if the OncoRad radiologists are able to accommodate the rushed request.
- Fee for providing a new or second baseline (e.g., when a patient crosses over to a new study drug or when a subject continues on study therapy beyond progression).
- Fee for re-reviews and corrections required due to insufficient or incorrect information in the protocol or read request, or protocol changes that were not reported to OncoRad.
All prices are subject to change without notice.
UW Oncorad pricing is changing effective 12/1/2016. If you have questions or need more information, please contact our Oncorad/TIMC Program Manager, Danielle Nacamuli, firstname.lastname@example.org.
OncoRad Help Desk – email@example.com
Please email the OncoRad help desk for additional information regarding OncoRad/TIMC:
The sponsor, PI and study staff are expected to understand the evaluation criteria in the protocol and are responsible for pointing out any modifications to the standard criteria. OncoRad personnel are responsible for reviewing the imaging section of the protocol for comparison with the standard published evaluation criteria but are not responsible for reviewing the entire protocol.
Effective 9/1/16, all protocols submitted to OncoRad must be accompanied by the UW OncoRad Protocol Registration Agreement (UW NetID required). If you are able to complete the form in advance, upload a scanned copy of the completed form to your protocol submission. We want to ensure that your protocol is not delayed pending signature. If you are unable to complete the form in advance you have 30 days to submit it via email to firstname.lastname@example.org. Failure to respond within 30 days of the protocol activation in OncoRad is agreement. After 30 days you will be charged for any modifications to the evaluation criteria: another protocol setup fee will be charged, and you will be charged for the re-review of any scans that have been completed.